…worrying the world. The reason is quite simple: much of what we know so far is fragmentary and suspect. The media loves to fan the flames of panic, anyway. But some is just lack of basic understanding as the authorities try to track its spread, plus skepticism about whether Chinese authorities have been forthcoming on this topic.
Out-of-control pandemics are the stuff of scary movies, but there are many times in human history when they have occurred. The 20th Century’s most enormous and out-of-control pandemic occurred right at the end of World War I and involved flu (I wrote about it here), the scope of which is difficult to comprehend even now. It is a terrifying prospect.
But each time a new flu comes along – and they come along with great frequency, often in China because of the vast urban populations and the close contact with animal vectors – it is hyped as the next enormous pandemic. Some day that may become true. But so far the flu pandemics of recent years, although they can do great damage (I had a friend who nearly died of H1N1, for example), have never reached anywhere near the scope of the 1918 pandemic. Fortunately.
So I will bide my time and see what happens before I hit the panic button that lies close at hand.
In the meantime, to learn about flu origins and China, see this from 2017:
Many Chinese people, even city dwellers, insist that freshly slaughtered poultry is tastier and more healthful than refrigerated or frozen meat. This is one of the major reasons China has been such a hot spot for new influenza viruses: Nowhere else on earth do so many people have such close contact with so many birds.
At least two flu pandemics in the past century—in 1957 and 1968—originated in the Middle Kingdom and were triggered by avian viruses that evolved to become easily transmissible between humans. Although health authorities have increasingly tried to ban the practice, millions of live birds are still kept, sold and slaughtered in crowded markets each year. In a study published in January, researchers in China concluded that these markets were a “main source of H7N9 transmission by way of human-poultry contact and avian-related environmental exposures.”…
These areas—often poorly ventilated, with multiple species jammed together—create ideal conditions for spreading disease through shared water utensils or airborne droplets of blood and other secretions. “That provides opportunities for viruses to spread in closely packed quarters, allowing ‘amplification’ of the viruses,” says Benjamin John Cowling, a specialist in medical statistics at the University of Hong Kong School of Public Health. “The risk to humans becomes so much higher.”
All flu viruses probably originate in birds, and the best environment for making the jump to humans is one where densely packed people live closely with birds and animals.
“In Asia we have a huge animal population, a huge bird population and two-thirds of the world’s people living there,” said Klaus Stohr, chief influenza scientist at the World Health Organization.
The population of China alone is bigger than that of the whole of Africa, and 80 percent of the new human flu strains the last few decades appeared in China first.
Did the new coronavirus originate in birds? We don’t know:
On 31 December 2019, a novel strain of coronavirus, officially designated as 2019-nCoV by the World Health Organization, was reported in Wuhan, China, as responsible for the 2019–20 Wuhan coronavirus outbreak. By 24 January 2020, 25 deaths have been reported and 547 confirmed cases. The Wuhan strain has been identified as a new strain of Betacoronavirus from group 2B with an ~70% genetic similarity to the SARS-CoV. The virus was suspected to have originated in snakes, but many leading researchers disagree with this conclusion.
More on the disease’s origins:
The initial cluster of pneumonia-like cases showed up in the city of Wuhan mid-December, and most of those patients had some tie to a wet market there—a place where people sell both live and dead animals, including exotic species, from snugly-abutting stalls.
Though nothing has been confirmed, epidemiologists suspect that the novel coronavirus crossed over into humans somewhere inside the market, which has been shuttered since January 1. Tracking down the right viral culprit is paramount to preventing future interspecies spillover. In 2003, when SARS ipped through the same area of China, the outbreak was fully contained only when civet cats, which had passed the virus along to humans, were removed from the region’s markets.
A national task force of Chinese researchers working swiftly to isolate and sequence the virus shared a draft of its genome in a public database earlier this month.
The article goes on to say that a theory based on the DNA evidence indicated that the virus may have originated in snakes, but there’s been tremendous disagreement with that idea:
“It’s complete garbage,” says Edward Holmes, a zoologist at the University of Sydney’s Institute for Infectious Diseases and Biosecurity, who specializes in emerging RNA viruses, a class that includes coronaviruses like 2019-nCoV. Holmes, who also holds appointments at the Chinese CDC and Fudan University in Shanghai, is among a number of scientists who are pointing out—in virology forums, science Slacks, and on Twitter—what they deem to be major flaws in the paper, and calling on the journal to have it retracted. “It’s great that viral sequence data is getting shared openly in real time,” says Holmes. “The downside is then you get people using that data to make conclusions they really shouldn’t. The result is just a really unhelpful distraction that smacks of opportunism.”
Preliminary analyses of the genetic data released by Chinese authorities suggest that 2019-nCoV is most closely related to a group of coronaviruses that typically infect bats. But for a variety of reasons—including that it’s winter and bats are hibernating—many scientists suspect that some other animal moved the virus from bats to humans.
We don’t know. And the other thing we don’t is how many humans will be infected, and what the death rates will be. Flu tends to kill a not-insignificant percentage of its victims, but usually the vast majority survive. In 1918, the flu was especially deadly not only because it infected huge numbers of people worldwide, but because it killed a higher percentage of those sickened, it often killed them very quickly, and it seemed to focus on an unusual group: 20- to 40-year-olds.
Let’s hope this one is much tamer, although the behavior of Chinese authorities doesn’t indicate business as usual for the flu. Then again, maybe they are just especially determined not to let this one get out of hand. Let’s very much hope it does not.
